Support Your Immune System: L-Lysine

Torricelli, P. People with high blood pressure should also consult a health professional before use. Also known as "L-lysine," lysine supplements are touted as a natural remedy for a number of health problems, including cold sores (herpes simplex labialis), genital herpes, and shingles. Laeger 10-22-1979;141(43): Thein DJ, Hurt WC. 10 best immune system supplements, ” Eating your five a day of fruits and vegetables is the best way to maintain necessary levels. Echinacea is one of the best known herbs in the United States and has hundreds of years of historical use as a folk remedy. Dietary L-lysine and calcium metabolism in humans.

Sulochana KN, Rajesh M, Ramakrishnan S. Griffith RS, Norins A, Kagan C. How to boost immunity naturally with 5 key tips! Thank your immune system, which defends you from disease-causing microbes. The following information will help you achieve a strong and balanced immune system: L-lysine undesirably lowers arginine levels, and since cats can’t synthesize the amino acid themselves, an arginine deficiency can result in hyperammonemia. A deficiency of lysine can lead to: Dermatologica 1978;156:

As a result, healing capacity and the ability to defend against infection becomes weaker.

People recovering from burns or other severe injuries and individuals doing frequent, high-intensity workouts may benefit from a higher-than-average daily intake of lysine. Kidney disease: Consuming lysine-rich foods, applying lysine ointment or taking a lysine supplement strengthens the immune system. A study in rats with diabetes found that lysine supplements could prevent the development of cataract ( 22 ). By exerting strict control over herpes virus, this essential amino acid also controls the spread of genital herpes. Lysine has no known mild interaction with other drugs. Griffith RS, Walsh DE, Myrmel KH, et al. When it comes to alternatives to L-lysine for the management of the feline herpes virus, consider the following tips.

View abstract.

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Still have questions? 2020 May;28(5): Lysine prophylaxis in recurrent herpes simplex labialis:

2020 Aug;34(8): Insulin receptor tyrosine kinase activity in monocytes of type 2 diabetes mellitus patients receiving oral L-lysine. Recently, there has been skepticism that supplementation with large doses of calcium is healthy. Rather than being shuttled straight to the walls of the blood vessels (where you don’t want it), the amino acid appears to induce the body to store calcium elsewhere, including the bones. Lysine has no known severe interactions with any drugs.

  • Almost all vitamins are involved in maintaining immune defenses on some level.
  • L-carnitine also helps protect cells from oxidative stress and contributes to the protection of nerve cells.
  • Unni US, , Raj T, , Sambashivaiah S, , Kuriyan R, , Uthappa S, , Vaz M, , Regan MM, , Kurpad AV.

Health Benefits

Side effects Scientists have found that this amino acid can reduce blood sugar levels in patients with type 2 diabetes. For example, it has been shown to prevent the buildup of calcium in blood vessels in rats. Lysine can be given as a supplement to both humans and their pets. Reducing renal accumulation of single-chain Fv against melanoma-associated proteoglycan by coadministration of L-lysine. Flu fighting nutrition: give your immune system a boost, simple, holistic tips to fight illness and strengthen your immunity PLUS what you can do if you do get sick, to fight it quickly. The group of rats that were fed the l-lysine had fewer loose stools, indicating a lower stress status. I purchased this as an alternative to the nasty maple-flavored Viralys gel.

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To improve glutathione synthesis, cysteine should be taken together with vitamin C. Lysine has no known moderate interactions with any drugs. Alcohol (40%), Distilled Water.

If your order is selected for review, our Loss Prevention Team may contact you by phone or email. Lysinuric protein: They found that when people were fed more lysine, they had lower levels of the stress hormone cortisol and improved mood – a great result. Infusionsther. Lysine is used to support the body’s ability to absorb calcium, building stronger bones and preventing osteoporosis. L – Lysine consumption is also said to protect you from hair loss due to its collagen formation ability and anxiety controlling effect. The feline herpes virus needs the amino acid arginine to reproduce.

Blocking of the receptions disrupts the brain’s ability to respond to stressful stimuli, helping a person feel more relaxed in situations that would otherwise have been a source of worry.

Lysine Restriction Influenced Anti-inflammatory Cytokines

Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis. Here are other areas where lysine may benefit your health: Dermatologica 1987;175: Salmon, cod, and tuna Dairy: However, when combined with lysine, calcium loss is reduced, an indication that lysine plays a vital role in helping the body to hold onto its calcium reserves. Health benefits and risks of plant proteins.

Echinacea and lysine supplements both show potential for health promotion and disease management, but can also have side effects.

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Good sources of this essential amino acid include fish, eggs, cheese, lima beans, potatoes, red meat, milk, yeast, and soy products. Vitamin A helps regulate immune function. It is also helpful for calcium absorption, which supports strong bones, and it helps promote healthy skin. Collagen is a vital scaffolding material that skin uses to repair over a wound.

It functions as an immunoregulator and, together with glutathione, forms one of the most powerful antioxidants. 50% of the population do not get the recommended daily allowance of vitamin E. It is safe to take vitamin C in doses of up to several grams per day.  There is not enough evidence to know if it is safe for women who are pregnant or breastfeeding. This label will contain vital information including the amount of active ingredients per serving, and information about other added ingredients. This study went on to demonstrate that L-lysine was an ineffective management tool for treating symptoms or flare-ups of FHV-1, and may even make the infection worse.

However, L-carnitine also plays a major role in the immune system. The daily dose for treatment of an active herpes simplex infection should be 3,000 mg per day. It’s naturally found in food and is the type used in supplements. Acta 1987;46(11): Finally, supplementation with lysine has been shown to reduce mood imbalances and even cortisol levels in those who consume low amounts of lysine. L-cysteine can contribute to the elimination of heavy metals.


Research supports that lysine can reduce the healing time of cold sores when applied as a lysine ointment. Lysine and the herpes virus Arginine is an amino acid which encourages the Herpes Simplex Virus (HSV) to replicate. For returns via mail, you must carefully package the product, you are responsible for the cost of return shipping, and we must physically receive the return within the 60 day period.

These results showed that lysine restriction affect inflammatory response via mediating serum antibody volume, inflammatory cytokines, and Tlrs.

A 1984 study, published in Archives of Dermatology, explored the use of oral lysine supplements (400 mg, three times per day) in a group of 21 patients with recurrent herpes simplex infection but did not find a substantial benefit of lysine treatment for prevention or treatment. IN CASE OF ACCIDENTAL OVERDOSE, CONTACT A HEALTH PROFESSIONAL IMMEDIATELY. Smriga M, Ghosh S, Mouneimne Y, et al.

Many take l-lysine supplements because it can enhance the size and shape of the muscle.

Trials have failed to prove the efficacy of L-lysine supplements. 2020 Dec 23;100(26): 2020 Oct;38(5): Potatoes, peppers and leek Fruits: Taking lysine in combination with L-arginine is recommended. Is there any hard evidence for this?

Is L-lysine no longer the forerunner in treating FHV- 1?
  • 400 mg – 600 mg per day, cysteine is a medication you can get without a prescription to facilitate active transport across mucosa.
  • Lysine for management of herpes labialis.
  • A L-lysine allergy may occur causing uncomfortable side effects.
  • Does L-lysine have no side effects?
  • Collagen is also an essential component of the repair process of our bodies after injury.

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There may be a two business day delay to process your order. According to European agencies, the recommended daily allowance of Vitamin C for a healthy, young non-smoker is 80 mg. This kind of buildup is a risk factor for heart disease ( 13 ). Eating disorders linked to immune system diseases, primary immunodeficiency diseases can occur in individuals of any age. Dietary requirements of synthesizable amino acids by animals: Histamine is released in allergic or asthmatic conditions and is the cause of allergic symptoms. Effect of lysine hyaluronate on the healing of decubitus ulcers in rehabilitation patients. Lysine helps pets produce antibodies and enzymes that support the immune system.

DiGiovanna JJ, Blank H. Many people who suffer from cold sores also choose to take lysine supplements as well. Bodybuilders love l-lysine. Cutis 1984;34:

Lysine is an essential component of all proteins and works with other essential amino acids to maintain growth, lean body mass, and the body's store of nitrogen. Topical application of a lysine ointment has also been explored for herpes simplex infections. Our customers love to take our Ester-C® and L-Lysine together for a healthy immune supporting duo. Lysinuric protein intolerance: J Anim Sci Biotechnol. In the past, administering L-lysine for cats was thought to be helpful in fortifying the immune system, while warding off respiratory infections – specifically, feline herpes virus, also known as FHV-1. This is not an indication of a security issue such as a virus or attack. Interestingly, the study observed reduced cold sore breakouts when a person’s blood lysine measure was kept above 165 nmol/l.

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However, the women who also received 400 mg of lysine lost less calcium through their urine ( 14 ). Pfapa syndrome, they’re a type of white blood cell. One study found that a daily supplement of 1,000 mg of lysine resulted in fewer cold sores in 26 people who were prone to recurrent cold sores. The pieces are large, so I broke it in two. It could even reduce the risk of calcium buildup in your blood vessels. The item must be returned, unused or used, in good condition, in original boxes (whenever possible), and with all paperwork and accessories to ensure full credit. Vitamin C controls histamine levels in the body.

Lysine is crucial for the formation of collagen, a major part of the body's connective tissues and appears to help the body absorb and conserve calcium and may reduce its excretion. Antiviral herbs: protect against viruses and how to use. Relation of arginine-lysine antagonism to herpes simplex growth in tissue culture. Vitamin D is rarely found in food and is synthesized in the skin through UV radiation.

Taking large quantities of lysine may reduce the body’s ability to move arginine through the system. As a result, 9 out of 10 central Europeans have a vitamin D deficiency. Proponents claim that lysine supplements can also boost the immune system, as well as aid in muscle repair. Consider the benefits of giving a Lysine supplement to your furry friend. In humans, it is often used to treat cold sores because it seems to stop the herpes virus from growing. Why is L-lysine beneficial for cats?  However, scientists have yet to determine if lysine supplements can help prevent osteoporosis in humans.


These unique immune health ingredients are combined in strategic doses to create an ideal immune support formula. ERKs and c-Jun N-terminal protein kinase (JNK) are members of MAPK family, which is associated with inflammation28. If in doubt, check with your doctor. Once infected, controlling HSV recurrences through diet is based on a person’s ability to regulate their lysine/arginine balance. 11 natural ways to boost your immune system, but to not have relief from the stress -- to be under constant stress -- is deleterious to health,” says Polsky. Dieticians and health professionals recommend including calcium rich foods in our day-to-day diet to maintain our bone strength; however, just consumption of calcium rich foods is not adequate to ensure your bone health. Your daily values may be higher or lower depending on your calorie needs.

Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. It also helps support respiratory health and helps maintain normal eye function and health. Evidence shows that eating foods rich in lysine or taking lysine supplements decreases blood sugar levels and increases insulin secretion in people who do not have a healthy blood sugar balance. Calcium is an important mineral that needs to be absorbed and retained by our body to fully extract its health benefits. I was hoping I could just get Serena to eat a couple of treats a day to build up her immune system. There is not enough information about the safety of taking lysine if you are breastfeeding or pregnant. AOR’s L-Lysine offers a safe and effective dose of high quality, pure L-lysine.

The root of a L-lysine allergy is quickly addressed and resolved by removing the L-lysine from the cat’s diet altogether. Hall SL, Greendale GA. Lysine has antiviral properties and is recommended as an inhibitor of herpes viruses and shingles (herpes zoster). 2020 Dec;31(6): Lysine supplements from trusted brands can bring balance to your body, strengthen your immune system and help in exerting control over your anxiety and stress level. 15 foods that boost the immune system, it isn’t easy, but the future of your health depends on it. 4 mins, 17 secs.

  • Our previous study has revealed that lysine deficiency induced apoptosis5, which is highly associated with inflammatory response29.
  • Studies have shown that taking high doses of zinc in combination with vitamin C can cut the duration of a cold in half.
  • Your healthcare provider can provide recommendations regarding dose and proper use.

Advanced Formula for Immune System Support

Smokers need twice the amount of vitamin C that non-smokers require. Early research indicates that it may even help improve symptoms in people with schizophrenia. Possible complementary effects of such supplements include improved metabolism, anxiety and mental stress reduction and enhancement of immune and cardiovascular activities. Incorporating key nutrition elements will help to strengthen the body's defenses. Vitamin E is a strong, fat soluble antioxidant. Am J Kidney Dis 1996;28: In this study, the mRNA abundance of IL-8 in the kidney and IL-6 in the spleen were significantly higher in the lysine-restricted group compared with the control group. Vitamin C (ascorbic acid) is the most well-known and researched supplement.

The Bottom Line

Practice aggressive preventative medicine and treat health conditions that do develop quickly to avoid “distracting” the immune system. Collagen builds connective tissues, cartilage, and bones. We proudly offer international shipping to over 180 countries and several US Territories. The women given 3 grams of calcium alone had a progressive increase in calcium in their urine. If you are not completely satisfied with an item you’ve purchased, you may return the item within 60 days from the order date for a full refund of the purchase price, minus shipping and handling*. Since it is naturally abundant in high protein foods such as meat, eggs, beans and legumes, those most likely to suffer from deficiency are vegetarians or vegans who consume a diet low in legumes and high in grain-based foods. Lysine helps in the formation and prevents the breakdown of Collagen. When you buy a lysine supplement, (or any dietary or herbal supplement) the National Institutes of Health (NIH) recommends that you look for a Supplement Facts label on the product that you buy.

It is an amino acid that serves as a building block for protein, which plays a key role in carrying out many different bodily functions. Effect of lysine, , vitamin B(6), , and carnitine supplementation on the lipid profile of male patients with hypertriglyceridemia: Pine bark extract has a high content of proanthocynadins, which can help the body process vitamin C and E.

Why take chances when you can get the best support for your immunity? Stressful situations often weaken the immune system, which can give the virus an opportunity to take over. Five tips for building a better immune system, on the contrary, news websites ranked high, as their frequency in the top 10 was twice that in the total search. Iron is another contributor to effective functioning of the immune system.

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Use of complementary and alternative medicine for the treatment of genital herpes. However, one study found that applying a gel containing lysine to an ulcer wound resulted in reduced infection and faster healing time than when no gel was used ( 20 ). Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion. However, the connection is still unclear ( 23 ). Why do stress hormones suppress the immune system? Information about the light/dark cycle is transmitted from the retina to the paired suprachiasmatic nuclei in the hypothalamus. As a rough guide, scientists recommend taking between 500mg and 1,500 mg daily for the prophylaxis of herpes simplex, ideally in combination with zinc and vitamin C. The harder you exercise, the more HGH the body releases and the better you’re able to recover. Numerous studies have demonstrated that the intake of amino acid affect the inflammatory responses of animals7,10. Treat especially severe flare-ups with antiviral medications and secondary bacterial infections with antibiotics.

Facts and fallacies of purported ergogenic amino acid supplements. We also found that lysine restriction markedly decreased the abundance of IL-4 in the kidney and IL-10 in the liver, but significantly increased the abundance of IL-4 in the spleen. Lysine appears to protect your bones and may also play a part in controlling whereto calcium is transported in your body. For your protection, all orders are screened for security purposes. The scientists then exposed the rats to a stressful situation and looked to see whether there were any differences in the two groups’ bowel movements.

Scientific Reports

(2 pounds) of wheat flour in deprived villages in Syria helped reduce anxiety scores in males with very high stress levels ( 8 ). With continued administration, this supplement helps support a healthy, happy cat. What to expect while breastfeeding, women hear a lot of conflicting information about what they can or cannot eat while breastfeeding and these recommendations may vary according to culture and tradition, along with individual personal preference and finances. Selenium can help slow the proliferation of viruses and boost the immune system.

A lack of L - Lysine can lead to protein deficiency syndrome and adversely affects our immunity strength. This gives the body a chance to recycle these antioxidants on an as-needed basis. The serum antibody volume has been widely used to evaluated the humoral immunity12. Civitelli R, Villareal DT, Agnusdei D, et al.  Various doses have been studied in research. To create and edit your shopping list , sign in to your account. As our body is incapable of synthesizing lysine on its own, this essential amino acid must be provided through a well-balanced diet or a healthy dietary supplement. Calcium leeches out of the bones into the bloodstream and then gets excreted by the kidneys, flushing it out of the body.