How Marijuana Suppresses The Immune System

This isn’t to suggest that smoking marijuana can cure cancer, as some have said. The most recent research suggests that, to date, states with medical marijuana laws have not seen an increase in adolescent use. A 2020 study found that, after giving participants 50 milligrams of THCA every day for one month, no THC was found in the hair specimen samples, but THC-COOH was still detected.

An agonist is a drug that attaches to the same receptor as a natural chemical and causes the same effect. Today, the different causes of autoimmune diseases are still greatly unknown. Boost your immunity: cold and flu treatments suppress innate immune system. In order to comprehend how a single cell reacts to these molecules, we first need to understand the purpose of ECS.

It is believed that the immune system also plays an important role in neurodegenerative and neuroinflammatory conditions, such as head injuries, stroke, and cerebral ischemia (a condition where there is insufficient blood flow to the brain).

However, this study revealed that even short-term marijuana use can help these important cell groups stay healthy and strong. This is where the runny nose, sore throat and achiness come from. There is added concern because adolescence is an important time in development when young people’s brains are building the connections to improve executive functioning (e. )Even if someone who suffers from addiction does not develop more serious problems, like cognitive problems, heart disease, lung disease, or liver failure, harm done to the immune system can lead to serious, recurring, or incurable infections. And given that parents, not to mention the federal government's war on drugs, are trying to get kids to "just say no" to marijuana, Melamede's company will face an uphill climb. In 2020, in the U. The ECS regulates a plethora of physiological processes, including immune function and inflammation.

The plant’s anti-inflammatory properties can help you cope with symptoms like sore throat, sinus pain and body aches. Research is key, but it can’t move fast enough to unlock the genetic codes to stop, prevent or cure the increase in diagnosed cases every year. What we do know, however, is they tend to be hereditary and run in families. High amounts of THC can increase the risk for negative effects. Smoking pot may also reduce the respiratory system’s immune response, increasing the likelihood of the person acquiring respiratory infections, as well as pneumonia and emphysema. 4 aromatherapy recipes to boost your immune system, when I feel something coming on I immediately take a couple onGuard Beadlets or Softgels and start diffusing as well (these can also be used 2 weeks prior to returning to school to boost immune system). An annual survey conducted in the United States from 1975 to 2020 documented that marijuana is now the second most commonly smoked substance after tobacco (1,2). For the unacquainted, viral load is a term used to describe the number of HIV’s ribonucleic acid (RNA) copied in a patient’s blood.

According to a review of animal studies, cannabis use might lead to sexual dysfunction.

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He, too, said he has self-tested his lozenge. These symptoms include being irritable or restless, having a small appetite, experiencing cravings, and problems with mood and sleep. Two recent studies support the findings that cannabis could improve immune function for people with HIV/AIDS. A healthy immune system balances an aggressive response to harmful intruders with a tolerance for “good” bacteria. 6 ways to boost your immune system naturally, wBCs are the body's immune system cells that fight disease. For most people, these infections are mainly a bad nuisance, though they can problematic for young children, the elderly and other at-risk groups, such as people with compromised immune systems. Misinformed people tend to perceive inflammation as a negative occurrence, but the truth is not that straightforward. Patients with Parkinson’s disease reported a reduction in tremors and better motor control. This is because HIV/AIDS is one of the most common viruses to effectively attack and compromise the human immune system.

Recent research suggests that THC might also protect neurons from trauma.

Central Nervous System

An international team of immunologists studying the effects of cannabis have discovered how smoking marijuana can trigger a suppression of the body's immune functions. There’s already promise in marijuana for autoimmune disease. These frontline defenders block and filter out pathogens and damaging bacteria. Unlike the instances of suppressing our organism’s defenses, there are cases where cannabinoids can do the exact opposite—strengthen our immune system.

It acts on specific brain receptors, causing possible mood changes, depression, suicidal thinking, memory issues, and disruption to normal learning abilities. Coronavirus and immune system, there is evidence that green tea and chamomile tea can help strengthen the immune system. Those currently treating autoimmune disorders with cannabis would be advised to monitor their progress closely and to do so with the help of a qualified medical professional. Besides humans, all vertebrates have this system, alongside many other non-vertebrate life forms.

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While these cells help the body fight infections, no direct link with lowered immunity has yet been shown. But obviously it’s something that should be studied in greater detail. THC is the key mind-altering (psychoactive) substance in marijuana. The active compounds in cannabis are not only responsible for the herb’s psychoactive effects. In the hippocampus, THC changes the way you process information, so your judgment may be impaired. More research is needed.

For instance, Type 1 diabetes can cause symptoms like: Cannabis can also help with depression. Although the federal government still lists marijuana as a Schedule I drug, a class “with no currently accepted medical use,” a body of recent research—most of it done in test tubes and animals, but some done in people—suggests that cannabinoids, which are the active ingredients in marijuana, may have medicinal uses even beyond the approved ones. One study found that marijuana directly affects a type of cell called myeloid-derived suppressor cells, which suppress the immune system’s response in certain situations. Over the past decades, the typical percentage of tetrahydrocannabinol (THC), the most active ingredient in marijuana, has increased in marijuana and marijuana products, making them more potent. Here’s what we know so far.

The HIV/AIDS virus incapacitates the primary defenses of the immune system by attacking collections of certain cells known as CD4 and CD8.

Multi-disciplinary Sciences

In addition, the celebrated pharmacological properties of cannabis have led thirty-six states to permit its use as a therapeutic drug for, among others, those suffering from AIDS; various painful, incurable and debilitating illnesses; the harmful side effects of cancer chemotherapy, and glaucoma. Biogaia probiotics, our professional staff is ready to help you. In a 2020 review authored by Paul Cary, director of the Toxicology and Drug Monitoring Laboratory at the University of Missouri, Cary stated that THC detection times rarely exceeded 30 days, occurring in a select few cases. As much as possible, eat organic food. Marijuana smokers, when compared to non marijuana smokers, have more respiratory illness. However, sometimes the immune system needs to be suppressed. Also, spurs creativity and helps manage pain and fatigue. However, the lack of filtering and differences in the smoking technique associated with marijuana use result in an approximately fourfold greater deposition of tar particulates in the lung than occurs from smoking similar amounts of tobacco (6).

The amount of THC (the active ingredient) in marijuana and marijuana products has increased greatly over the years. The researchers found that marijuana triggered the production of a massive number of myeloid-derived suppressor cells — leading to immune suppression and cancer growth — by activating cells that respond to the cannabinoids found in marijuana, researchers said. How to boost your immune system: 12 tricks that work, caring for Skin, Nails, Hair and Mouth from The Leukemia & Lymphoma Society (LLS) for more healthy lifestyle tips. Even in low doses, smoke can cause significant irritation and inflammation of the lungs while also compromising any remaining pulmonary defenses to additional infection. ‘This hypothesis, though, cannot be tested as NHANES does not collect information on cannabis use motives. It may well be that cannabis provides the relief that patients need; however, only time will tell exactly how its benefits work on the body. Proclaimed the wonder cancer treatment of the future, immunotherapy retrains white blood cells to detect and kill cancer in the body. But once you grasp the connection, your sense of awe for how our organism works will rekindle. The study concluded that the drugs tested were safe, but did not improve Parkinsonian motor disability.

These symptoms can last up to two weeks after the last use.

History of Autoimmune Disease

Only one drug at the moment is showing effective in slowing the advancement of ALS, and doctors are prescribing a host of medications for all other autoimmune disorders that can bring some relief or retard the downward spiral of many others. My scientific area of expertise is called immunotoxicology. One of the ways cannabinoids influence the ECS is by stimulating a specific response from the immune system. Eases pain, stress, insomnia and depression. Acute memory loss: Understanding the biology and chemistry behind marijuana's claimed medical benefits is becoming extremely important now that 23 states and the District of Columbia allow the use of marijuana to treat some medical conditions, including pain, nausea and glaucoma.

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Signs that someone might be addicted include being unable to stop using marijuana, using it even though they know it is causing problems, and using marijuana instead of joining important activities with friends and family. The infants may end up with skin rash, a heart defect, liver problems or low blood count. Studies suggest that a combination of individual counseling and group therapy sessions is the best approach for stopping marijuana use. Despite cannabis having the ability to suppress the immune system in healthy individuals, recent research suggests that it can actually strengthen the immune response in individuals with a weakened immune system.

Take at the first signs. In most scenarios, though, treating and reducing the inflammation is the important goal. Six ways to boost your immune system to fight corona virus: deepti saxena, md: family medicine. It may feel like running on caffeine is a good plan, but it will catch up with you! Doesn’t it seem like a new, potentially beneficial medical use for cannabis seems to be discovered every few months?

Emma Stone

Medical marijuana is not subject to governmental standardization, making its ingredients and potency unknown. Cannabinoids and the immune system: In a study conducted by researchers at universities in Virginia and Florida, CD4 and CD8 white blood cell counts were compared in a sample of 95 HIV patients, some of whom were chronic cannabis users. People with low immunity, the cold or flu allowed the body to cleanse itself and the immune system becomes stronger to fight future infections. Cannabis can be combined with other super foods like turmeric to boost its anti-inflammatory properties.

The scientific literature contains occasional hints that the pharmacology of pure THC, although similar, is not always the same as the clinical pharmacology of smoked marijuana containing the same amount of THC (Graham 1976, Harvey 1985, Institute of Medicine 1982)" (Report to the Director, National Institutes of Health, by the Ad-Hoc Group of Experts, "Workshop on the Medical Utility of Marijuana.

What is medical marijuana? At the federal level, marijuana is still illegal regardless of use—it is classified as a Schedule I drug (i. )This can include the heart, brain, muscles, digestive tract, skin, eyes, joints, nerves, and lungs. Stress, illness and the immune system, the brain and the immune system are in constant communication in this delicate balance that can be disrupted by any kind of physical or emotional stress. What is known today is that cannabis has the ability to “modulate” how the immune system functions, but its potential benefits or drawbacks are largely circumstantial. However, anyone who uses marijuana may suffer from negative health effects, such as testicular cancer, heart attacks, respiratory disease, a weakened immune system, pregnancy complications, and low birthweight.

Scientists know that plant cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD) impact our health by interacting in different ways with the endocannabinoid system. Studies have not clearly supported the use of marijuana for PD. Herbs work best if you’re taking care of yourself in other ways too.

THC also connects with receptors on nerve cells in other parts of the brain that affect thinking, memory, coordination, and concentration.

Types of Autoimmune Disease

There are also anecdotal reports from California cancer patients who maintain that they benefited by combining immunotherapy with a low-dose, CBD-rich cannabis oil regimen under a doctor’s supervision. Physiological effects of marijuana include an alteration of heart rate. For example, the National Institutes of Health Adolescent Brain Cognitive Development (ABCD) study is gathering a large sample of data across several sites and over many years. The adaptive immune system has two key mechanisms: Another primary component of marijuana is delta-9-tetrahydrocannabinol (THC). Generally, in experiments actually using marijuana, the assumed dose of marijuana was based only on the concentration of THC in the plant material. As with marijuana and crack cocaine, smoking cigarettes can lead to upper respiratory problems and a lowered immune system response to infections in that area. Being told to stay positive when you’re not feeling it can seem like you’re expected to suppress your feelings.

Autoimmune Diseases and Medical Marijuana Research

New research goes even further in answering the question, does cannabis affect your immune system? The full extent of the long-term health risks of chronic cannabis use is currently unknown. In addition to physical health effects, marijuana use also is linked with cognitive problems; low academic achievement and other educational outcomes; impaired social functioning; and mental health disorders, including depression and anxiety. THC has been the focus of the bulk of research. In cases of over-activation, the immune system produces antibodies in response to an unknown trigger that attacks the body's own tissues and organs. White blood cells are the cells in our body that function mainly as immune cells – originating in the bone marrow. Some researchers think that cannabis might be neuroprotective— saving neurons from damage caused by PD. Cannabinoids (the drug molecules in marijuana) have also been studied for use in treating other symptoms, like bradykinesia (slowness caused by PD) and dyskinesia (excess movement caused by levodopa).

  • What are the effects of medical marijuana use on the HIV/AIDS virus?
  • Research carried out on siblings suggested that long-term marijuana use could increase the risk of developing psychosis in young adults.
  • Research exploring the potential of cannabis as an autoimmune therapy is emerging.


Optimum immune function entails a complex balancing act that relies on constant communication between our immune cells, tissues, and organs. It may also produce dependency. Unfortunately, there are some medical experts (namely with the National Institute of Health and the Drug Enforcement Agency) who don’t completely agree with the idea that marijuana can provide an overall beneficial boost to the immune system. But, the peripheral blood cells from the marijuana users expressed significantly higher levels of cannabinoid receptor messenger RNA than blood cells from non-users. It has similar symptoms as SLE, and once you stop the medication, the symptoms tend to go away. Fights inflammation, depression, muscle spasms, pain and arthritis. Marijuana researchers have found enough evidence over the past few decades that they now deem cannabis as a safe product to use, even while using most other types of medications. 7 plant-based foods to boost your immune system naturally, red peppers are another vitamin C-rich source for fighting colds. Page reviewed by Dr.

Other states are expected to follow suit. Their study included the pain-relieving compound delta-9 tetrahydrocannabinol (THC). Some common types of autoimmune diseases include: And finally, while some small, uncontrolled studies have suggested there may be a link between pot smoke and lung cancer, the jury is still out on that possibility.